In their paper, “Helpful Lessons and Cautionary Tales: How Should COVID-19 Drug Development and Access Inform Approaches to Non-Pandemic Diseases?” Holly Fernandez Lynch and colleagues have present...

In lieu of an abstract, here is a brief excerpt of the content:Book Reviews Bibliography on Plato's "'Laws, "" 1920-1970: With Additional Citations through May, 1975. By Trevor J. Saunders. (New York: Arno Press, 1976. Pp. i + 60. $15.00) The Penguin Classics translator of the non-Socratic Laws, as Leo Strauss called them, has here compiled in a most usable way a thorough bibliography of books and articles about the Laws or parts of them. The section "Texts, Translations, and Commentaries" (...) properly excludes translations not made directly from the Greek. In previous centuries this would, also properly, have excluded many a famous or popular translation, such as Thomas Taylor's or Victor Cousin's, worked out from the text of M. Ficino's "first edition" in Latin. Given the state of the Greek text and the practice, inaugurated by Ficino, of improving upon the Greek in the translatioias, some notation about the literalness of the translations cited would have been of additional value. Section B, in thirty pages, is the largest and also deliberately the most selective in striving to limit itself to work concerned exclusively or primarily with the Laws. But it cannot avoid including much material about some aspect of Plato in general rather than about the Laws; this is especially true of the subsection, B1, on comprehensive accounts. Section B2, on the text and its tradition, has overwhelmingly more citations about the indirect tradition than about the texts themselves, an interesting indication of the current state of this question. The next subsections, to B12, divide according to subject matter. BI3 lists studies on the influence of the Laws. The last section, in twenty-four pages, is most valuable. It lists, by Stephanus page number, an abundance of discussions of individual passages from Book I through Book XII wherever these discussions, bibliographically speaking, may have occurred. Students of the Laws will be well served by, and most grateful to, Professor Saunders for this bibliography. I can only second the intent of his parting epigraph that sends us back to the study of the Laws themselves. But I must add that more explicitly detailed work appears to be required both on the difficulties the text itself presents to students of Plato (one thinks of A. Boeckh's analyses of the prose in Books I through III) and on those which arise when the Laws is contrasted--from the point of view of design and intellectuality--with those of Plato's works that are comparable, if not in number of pages, at least in scale of conception and monumentality. V. TEJERA SUNY at Stony Brook Science and Philosophy in Aristotle's Biological Works. By Anthony Preus. (Hildesheim and New York: George Olms, 1975. Pp. ix + 404. DM.88) A reciprocal influence between Aristotle's philosophy and biology--if it could be demonstrated through step-by-step criticism and not merely asserted in generalities about functionalism--might help to explain both, and might also itself be philosophically interesting ; for it should clarify Aristotle's concepts of form, essence, universal, and species-concepts which have been mercilessly jumbled in the traditional interpretations. With the failure of Jaegerian developmental analyses, we can hardly now hope for help from detailed chronology. But a general dating of Aristotle's biological interest to the Assos-Mytilene period, when he was already aged forty, is accepted by most people (though not by Jaeger who [463] 464 HISTORY OF PHILOSOPHY put it at the end, nor by Ryle who put it at the beginning of Aristotle's career) and is the basis of Anthony Preus's contention in this book. For if Aristotle began serious biology only in middle life we could expect a tension between the antiphenomenal metaphysics of the Academy, which he had just left after twenty years there, and the kind of philosophizing and explaining that might seem demanded by living concrete organisms. Preus sets out to show such a tension, claiming on page 1 that "in P. A. and G. A. sometimes the philosophical position is bent to fit the observed facts, and sometimes the observations are adjusted to fit the philosophical position." The reader may be assured at once that this appalling accusation (which is repeated in the publisher's blurb) is not... (shrink)

Three figures in the American Reformed tradition—the novelist Marilynne Robinson, the theocentric ethicist James Gustafson, and the biocentric poet Robinson Jeffers—treat the perception of beauty as the framework of moral discernment in ways that seem particularly significant for ecological ethics. Their work makes vividly concrete dimensions of Calvin's theology of creation that have been the subject of increasing theological attention over the past twenty-five years. By focusing on receptivity to natural beauty, their approach suggests a reorientation of the Christian ecological (...) conversation that would root responsibility in grateful awe rather than stewardship, and would substitute graced responsiveness for obligation. This shift away from duty, sacrifice, and self-denial has the prophetic potential to inspire life-way changes that have been hard to effect through caustic critiques of wasteful materialism or exhortations to just regard for generations as yet unborn. (shrink)

Argues that despite claims of self-styled 'postmodernists of resistance', postmodernism provides neither a viable educational politics nor a foundation for effective radical educational practice. In place of postmodernism, the bookoutlines a 'politics of human resistance' which puts the challenge to capitalism and its attendant inequalities firmly on the agenda of educational theory, politics and practice.

We develop a conceptually clear, intuitive, and feasible decision procedure for testing satisfiability in the full multi\-agent epistemic logic \CMAELCD\ with operators for common and distributed knowledge for all coalitions of agents mentioned in the language. To that end, we introduce Hintikka structures for \CMAELCD\ and prove that satisfiability in such structures is equivalent to satisfiability in standard models. Using that result, we design an incremental tableau-building procedure that eventually constructs a satisfying Hintikka structure for every satisfiable input set of (...) formulae of \CMAELCD\ and closes for every unsatisfiable input set of formulae. (shrink)

The Chairman of the Australian Law Reform Commission summarizes the discussion of in vitro fertilization (IVF) at the 1983 Mogul International Management Consultants Ltd. Conference on "Bioethics and Law of Human Conception in Vitro." Participants included IVF pioneers Patrick Steptoe and Robert Edwards, as well as other British physicians, scientists, sociologists, and moral philosophers. They raised questions about multiple embryo implantations, the risks and benefits of IVF, the ethical responsibilities of investigators, public policy and social control of IVF, threats to (...) the family and to genetic integrity, and the implications of IVF for determining criteria of personhood and the beginning of life. (shrink)

This paper is not about the medical condition of AIDS. Nor is it about the history of the condition since it was first reported in Atlanta, Georgia in 1981. It looks rather, at the catalogue of legislative and other legal responses to the spread of AIDS. The paper analyses the AIDS condition in its historical context. The hysteria accompanying the outbreak of AIDS is contrasted with the similar hysteria associated with other previous epidemics experienced in Australia over the past two (...) centuries. The paper categorises the responses of lawmakers to the condition, according to the approach taken; from 'full blast', through 'moderate heat' to 'low key' or an attempt to avoid or minimise legal intervention. It is suggested that the appropriate response should depend upon such factors as the present magnitude of the condition, its likely future course, the availability of cures and protections against its spread and objectives being sought by intervention. Unless these factors are taken into account gross over-reaction can occur, causing social disruption and much personal injustice. (shrink)

Evolutionary Biology has two principal explananda, fit and diversity (Lewontin 1978). Natural selection theory stakes its claim to being the central unifying concept in biology on the grounds that it demonstrates both phenomena to be the consequence of a single process. By now the standard story hardly needs reiterating: Natural selection is a force that operates over a population, preserving the better fit, culling the less fit, and along the way promoting novel solutions to adaptive problems. Amundson’s historical survey of (...) the concept of adaptation captures the idea succinctly: The phenomenon of adaptation is at the core of modern evolutionary biology. Natural selection, the mechanism universally regarded as the primary causal influence on phenotypic evolutionary change, is first and foremost an explanation of adaptation. (1996: 11) At the same time, it appears that the capacity of natural selection to cause adaptations cannot account for every feature of the nature and distribution of biological form. Reason to believe this devolves from the simple fact that the bearers of biological form are organisms and a salient fact about organisms is that each faces the tribunal of the environment as a corporate entity, not as a loose aggregate of independent traits. One consequence of this fact is that at each stage of its development from egg to adult an organism must be an integrated, functioning whole. Another is that for any form to arise in an organism at a time, it must develop from the materials and processes at the organism’s disposal. The requirement of integration and the processes of development that produce it leave their distinctive marks on form. It seems reasonable, then, to suppose that one might appeal to the processes of development and the principles by which they operate in explaining the nature and distribution of biological form. (See here Gould 1977; Rose and Lauder 1996). (shrink)

Two rotational bands have been identified and characterized in the proton-magic N = Z + 1 nucleus Ni-57. These bands complete the systematics of well-and superdeformed rotational bands in the light nickel isotopes starting from doubly magic Ni-56 to Ni-60. High-spin states in Ni-57 have been produced in the fusion-evaporation reaction Si-28(S-32, 2p1n)Ni-57 and studied with the gamma-ray detection array GAMMASPHERE operated in conjunction with detectors for evaporated light charged particles and neutrons. The features of the rotational bands in Ni-57 (...) are compared to those of neighbouring isotopes and interpreted by means of configuration-dependent cranked Nilsson-Strutinsky calculations. The two observed high-spin bands are considered signature partners and assigned to configurations with one 1g(9/2) proton and one 1g(9/2) neutron, resulting in an unambiguous understanding of the energetically favoured signature alpha = -1/2 band but a somewhat less satisfactory description of the signature alpha = +1/2 band. (shrink)

Recent studies suggest that a non‐isotopic in situ hybridisation (NISH) approach can be successfully employed to investigate the carrier status of female relatives in families of selected patients with Duchenne muscular dystrophy (DMD) or Hunter syndrome, whose diseases are due to a specific X chromosome deletion.Whilst the majority of metaphase spreads from normal females show specific hybridisation signals on both X chromosomes when tested with either dystrophin or Hunter gene‐derived probes, only one X chromosome in each metaphase spread will show (...) the relevant hybridisation complex in female carriers of deletions involving the dystrophin or Hunter gene.Thus, the NISH method can be a valuable diagnostic tool for the detection of the carrier status of female relatives of patients with X chromosome deletions. (shrink)

In an exploratory context, a qualitative approach was used to document perceptions of psychiatric advance directives among legal professionals and mental health professionals in Ontario and Quebec. A Web survey was administered and a qualitative analysis approach was used to explore attitudes towards PADs. It was found that legal and mental health professionals hold dif erent values related to clinical, ethical and legal issues, which may be related to their professional training. Among the advantages associated with PADs include their ability (...) to document a mentally ill individual’s clear wishes, respect autonomous choices and foster collaborative treatment. Reported disadvantages of PADs include the possibility of new circumstances arising, mentally ill individuals may not comprehend completing a PAD, and whether a mentally ill individual should be permitted to refuse treatment on ethical grounds. (shrink)